Endocrine Abstracts

IntroductionWe report a case of severe thyrotoxicosis due to a metastatic testicular tumor secreting human chorionic gonadotropin (hCG), known to have a TSH-mimicking effect due to alpha-subunits’ structural similarity.Case reportIn November 2020 a 38-year-old man was referred to our Department for thyrotoxicosis of unknown etiology. He had no family history of thyroid disease and his medical history had...

Aim of the study: recurrence or persistence of hyperthyroidism occur in 15-25% of cases after radioiodine therapy (RAI) in Graves’ disease (GD). Our study aimed to establish prognostic factors affecting RAI outcome and to investigate if a tailored dosimetric approach based on the application of the “effective biological dose” (BED) offered a higher chance of success.Materials and methods: our cohort comprised 365 GD patients (280 women and...

Obesity has become one of the greatest public health concerns and is known to be a major risk factor for cardiac, respiratory and metabolic diseases. Bariatric surgery is the most effective treatment for morbid obesity. According with guidelines, surgery is indicated for treatment of patients with BMI greater than 40 kg/m2 or above 35 kg/m2, with at least one obesity-related comorbid condition, such as as type 2 diabetes, hypertension, dyslipidemia, sleep...

Bariatric surgery is the most-effective treatment for morbid obesity, superior to medical treatment. Metabolic syndrome (MS) is a condition characterized by multiple major risk factors for coronary heart disease, diabetes, fatty liver, and several cancers; the main, diagnostic, components of MS are low HDL-cholesterol (<40 mg/dl in man, <50 mg/dl in woman), raised triglycerides (>150 mg/dl), blood pressure >130/85 mmHg, fasting plasma glucose >100 mg/dl and...

Background: So far, guidelines for bariatric surgery do no recommend the universal screening for thyroid diseases, except the TSH measurement in selected patients. However, a possible interplay between obesity (possibly complicated by obesity-related comorbidities) and thyroid diseases has been postulated.Objective: Aim of the study was to investigate the prevalence of thyroid diseases in a cohort of obese patients, evaluated for bariatric surgery. Metho...